A typical cheese slice has about 285 calories; size, crust, and toppings can push a slice above 300.
Per Slice Calories (Low)
Per Slice Calories (Typical)
Per Slice Calories (Heavier)
Basic Cheese
- ~107 g slice
- ~285 kcal
- ~12 g protein
Everyday baseline
Pepperoni
- ~100 g slice
- ~300–320 kcal
- ~13 g protein
Meaty classic
Thin-Crust Cheese
- Lighter dough
- ~200–260 kcal
- Crisp edge
Lighter pick
How Many Calories Are Typically In A Slice Of Pizza: Styles And Sizes
Most diners land between 250 and 350 calories per slice. The anchor point many menus mirror is the USDA cheese slice entry at 285 calories for about 107 grams, while a pepperoni slice averages a bit higher near 300 to 320.
| Style | Typical Calories Per Slice | Typical Slice Weight |
|---|---|---|
| Thin Crust Cheese | 180–260 | 80–105 g |
| Regular Crust Cheese | 260–320 | 100–125 g |
| Pepperoni, Regular Crust | 300–330 | 95–120 g |
| Deep Dish Cheese | 350–450+ | 120–180 g |
Slice size drives the math more than topping hype. Crust thickness, diameter, and whether the pie is cut into six, eight, or twelve wedges change the grams on the plate. Cheese volume and post-bake oil also nudge calories upward.
Portion planning gets easier once you set your daily calorie needs. With a target in mind, you can choose a smaller wedge, pick thin crust, or pair a slice with salad instead of stacking two heavy pieces.
What Actually Drives A Slice’s Calories
Slice Weight And Diameter
A 14-inch pie cut into eight yields smaller wedges than the same pie cut into six. The grams per slice drop when you add more cuts. That alone can swing a slice by 50 to 100 calories.
Crust Style
Thin crust trims dough mass, so calories drop. Hand-tossed or pan crust adds dough and oil, which raises energy density. Stuffed crust adds cheese at the rim, which bumps calories even if the center looks the same.
Cheese Load And Toppings
Moving from plain cheese to pepperoni adds cured meat fat. Veg-heavy pies add volume with fewer calories than extra cheese or sausage. Extra oil brushed on top will also raise the count.
Restaurant Vs. Frozen Vs. Homemade
Chain pies vary by recipe. Frozen brands list serving sizes by fractional slices, so one “serving” might be a third of a slice by your cut style. Homemade lets you pick lighter mozzarella, lean meats, and thinner dough, which shifts the range downward.
Real Numbers From Standard Entries
The widely cited cheese slice lists 285 calories, 12.2 g protein, and 35.7 g carbs for a 107 g slice. A pepperoni slice sits near 300 to 320 calories with ~13 g protein per similar weight. Thin-crust chain entries commonly sit near 200 to 260 per slice based on size and brand data.
See the detailed cheese entry and the pepperoni entry in USDA-based databases for context on macros and sodium. Both draw from standard reference lab data and chain submissions.
How To Estimate A Slice Without A Label
Step 1: Weigh The Slice
Use a small kitchen scale. If you’re out, estimate: a slice that feels like a deck of cards is near 100 grams; deep dish feels denser.
Step 2: Pick A Baseline
For 100–110 g, use 285 calories as a cheese baseline. Add 10–15% for pepperoni or sausage. Subtract 10–15% for thin-crust veggie if cheese looks modest.
Step 3: Adjust For Crust And Oil
If the rim is puffy and there’s visible oil pooling, bump the estimate by 30–80 calories. If the rim is crisp and flat with light cheese, drop by 20–40.
Step 4: Cross-Check With A Chain Entry
Many chains list nutrition per slice by pie size. A thin 14-inch cheese slice often lands near 200–210 calories in those listings, while deeper styles creep past 300.
Portion Moves That Keep Pizza In Your Plan
Pick The Right Size
Order a small pie so each wedge is lighter, or ask for an extra cut to turn eight slices into ten. That spreads the same pie across more pieces and trims calories per slice.
Go Thin On Crust
Thin crust drops dough grams fast. Pair that with a light cheese request and veggie toppings, and you keep flavor without pushing the count too high.
Balance The Plate
Team one slice with a side salad or broth-based soup. You’ll feel full with fewer total calories than two heavy slices.
Mind The Extras
Garlic butter, ranch, and stuffed edges add quick energy. A simple marinara dip keeps the taste without the extra oil.
Macro Snapshot By Common Slices
| Slice Type | Calories Per Slice | Protein |
|---|---|---|
| Cheese, Regular Crust (~107 g) | ~285 | ~12 g |
| Pepperoni, Regular Crust (~100 g) | ~313 | ~13 g |
| Cheese, Thin-Crust Chain | ~200–260 | ~9–12 g |
| Cheese, Deep Dish | ~350–450 | ~12–16 g |
Sodium, Carbs, And Protein At A Glance
That 285-calorie cheese slice often carries around 640 mg sodium with ~36 g carbs and ~12 g protein based on standard entries. Pepperoni lifts fat and sodium more than protein.
Want a step-by-step walkthrough? Try our calories and weight loss guide.